Nanoparticles liquid route
Description
This nanoparticle synthesis platform in solution consists of three batch or continuous flow synthesis devices, which can be coupled with SAXS, UV-Vis and Raman analyses. The first device is a synthesis reactor for volumes from 50 ml to 1 L, with automated control of temperature, pH, reagent injection and agitation. The second device is a thermostatically controlled reactor under continuous flow with control of the injection and mixing of the reagents via flow control. This device will in the future be coupled to a feedback loop to adjust the flow rates in real time during synthesis. The final device is a liquid handling robot to prepare hundreds of samples for subsequent high-throughput screening. Controlling the temperature and mixtures will make it possible to explore different synthesis and aging conditions of materials.
Localisation
CEA Paris-Saclay, NIMBE, LIONS, SWAXS Laboratory.
Contacts
Responsible for the platform: Mark LEVENSTEIN
Associated targeted project coordinator: Yann LECONTE
Technical characteristics
Batch reactor: Atlas Reactor (Syrris)
Temperature up to 250°C
pH control from 1 to 14 with an accuracy of ±0.2 pH
Volumes from 50 mL to 1 L possible
Heidolph Hei-Torque Stirrer
Injection of up to 2 different reagents if pH control is not used
Continuous flow reactor: Micro- and milli-fluidic devices
Syringe pump or pressure based injection of 2 to 4 liquids
Heating up to 100°C with the possibility of future hydrothermal upgrades
Flow rates from 50 µL/min to 10 mL/mi
Liquid handling robot: Flex (Opentrons)
Temperature control between 4°C and 95°C
Orbital shaking from 200 to 3000 rpm (room temperature to 95 °C)
Handles 12 96-well plates; Container sizes up to mL are possible