High-throughput platform for synthesis and characterization of polymers by flow chemistry
Description
The platform includes a flow chemistry reactor suitable for the synthesis of polymers in homogeneous solution by chain polymerization, involving the radical and ring opening pathways, or by polyaddition. This reactor is coupled to a high-throughput steric exclusion chromatography chain, i.e. capable of carrying out an analysis every ten minutes. The acquisition of a so-called “benchtop” 80 MHz NMR is planned for September 2024. This equipment will notably allow continuous monitoring of the conversion of the monomer during polymerization. The platform is supplemented by specific equipment allowing “off-line” characterization of the biodegradability of polymer nanodispersions, aerobically and anaerobically.
Location
LCPO Laboratory, UMR-CNRS 5629 Université de Bordeaux/Bordeaux INP
Contacts
Platform managers: Simon HARRISON
Associated targeted project coordinator: Jean-François GERARD
Technical characteristics
Flow Chemistry Polymer Synthesis System:
- Pressure up to 100 psi; Temperature Range: 20 – 150°C
- Characterization by SEC (RI detector, 80MHz NMR to come)
- Access to a glove box for preparing sensitive reagents
- Possibility of post-functionalization
High-throughput characterization platform:
Associated targeted project
